Fig. 8

Stratification of the ruminal resistome composition in study 2. a The principal coordinate analysis of the ruminal resistome showed four resistance types (resistotypes) among the 16 dairy cows. b The significantly different ARGs among the four resistotypes tested by LDA effective size analysis, with LDA > 2 being considered significantly different. Differential ARGs among the four ruminal resistotypes were only found to be enriched in Type1 and Type4. The heatmap shows the abundances (log10-transformed reads per million) of each differential ARG. * Represents the ARGs that were also found to be significantly different between high- and low-milk protein yield groups. ARGs: antimicrobial resistance genes