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Table 1 The 6 most prevalent antimicrobial resistance genes found in rumen and the characteristic of the antimicrobials to which they confer resistance

From: Characterisation of the rumen resistome in Spanish dairy cattle

Gene

Antibiotic class

Mechanism

Disease

macB

Macrolide

Efflux pump

Mastitis [12]

Metritis postpartum [13]

msbA

Nitroimidazole

Efflux pump

Genital trichomoniasis in cattle

Main growth-promoter [14]

parY

Aminocoumarin

Target alteration

Mastitis in dry dairy cattle [15]

rpoB2

Rifamycin

Target alteration and protection

Mastitis [16]

tetQ

Tetracycline

Target protection

Post-partum metritis

Lameness and mastitis [15]

TaeA

Pleuromutilin

Efflux pump

Mycoplasma in swine [12]