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Fig. 2 | Animal Microbiome

Fig. 2

From: Functional feeds marginally alter immune expression and microbiota of Atlantic salmon (Salmo salar) gut, gill, and skin mucosa though evidence of tissue-specific signatures and host–microbe coadaptation remain

Fig. 2

Keystone microbiota of Atlantic salmon associated with mucosal tissues and dietary treatments according to differential abundance testing and network analysis. A log2-fold-change plot (A) shows the results of pairwise differential abundance (DA) conducted between tissues, while controlling for diet using DESeq2 (FDR corrected q ≤ 0.05 and log2-fold change|≥ 1). Within tissue dietary effects were also tested, with only one dietary DA ASV identified (Gill: Control v. MOS) (A). Bacterial genera are listed on the y-axis, points are colored by phylum, and shape identifies the pairwise treatment comparison for which the ASV showed DA. Positive fold-changes indicate an increased abundance in the first group in the comparison, and vice versa. Microbiota networks (BD) depict the top 50 most connected ASV (nodes) according to sparse inverse co-variance networks reconstructed from the gut (B), gill (C), and skin (D) microbiota datasets. Network nodes are colored by phylum, while node size is positively correlated with Laplacian centrality, and edges are colored by positive (green) and negative (red) covariance relationships

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