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Fig. 5 | Animal Microbiome

Fig. 5

From: The influence of maternal unhealthy diet on maturation of offspring gut microbiota in rat

Fig. 5

OTUs significantly altered between groups. Microbial taxa among the top 100 OTUs identified to significantly differ in abundance between A mothers (Chow vs. Caf); B weanlings (Chow vs Caf), underlined OTUs indicate 9 common taxa between mothers and weanlings; C offspring at 7 weeks (ChowChow vs CafCaf); and D offspring at 14 weeks (ChowChow vs. CafCaf) by DESeq2 (padj < 0.05) and LEfSe (LDA Score > 2.0, p < 0.05). In DESeq2, negative (red) Log2foldchange value denotes decreased abundance and positive (green) Log2foldchange value denotes increased abundance in A Caf mother; B Caf weaner; C 7 week offspring in CafCaf group; and D 14 week offspring in CafCaf group. E Differential OTUs 7 OTUs and 30 OTUs were uniquely altered in Mothers and Weanlings by maternal Caf diet, with 9 common OTUs in Caf Mothers and Caf Weanlings. F Relative abundance of Ruminococcus_Otu00086 in 3-, 7- and 14-week offspring fed Caf diet compared with offspring fed chow diet. Note differences were significant using both LEfSe and DESeq2

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