Fig. 5From: The influence of maternal unhealthy diet on maturation of offspring gut microbiota in ratOTUs significantly altered between groups. Microbial taxa among the top 100 OTUs identified to significantly differ in abundance between A mothers (Chow vs. Caf); B weanlings (Chow vs Caf), underlined OTUs indicate 9 common taxa between mothers and weanlings; C offspring at 7 weeks (ChowChow vs CafCaf); and D offspring at 14 weeks (ChowChow vs. CafCaf) by DESeq2 (padj < 0.05) and LEfSe (LDA Score > 2.0, p < 0.05). In DESeq2, negative (red) Log2foldchange value denotes decreased abundance and positive (green) Log2foldchange value denotes increased abundance in A Caf mother; B Caf weaner; C 7 week offspring in CafCaf group; and D 14 week offspring in CafCaf group. E Differential OTUs 7 OTUs and 30 OTUs were uniquely altered in Mothers and Weanlings by maternal Caf diet, with 9 common OTUs in Caf Mothers and Caf Weanlings. F Relative abundance of Ruminococcus_Otu00086 in 3-, 7- and 14-week offspring fed Caf diet compared with offspring fed chow diet. Note differences were significant using both LEfSe and DESeq2Back to article page