Fig. 3

Microbial network analysis of the milk microbiota and their relative abundance. A The network is based on the combination of classical Spearman correlation-based network analysis corroborated with a GLM approach. Each node represents a taxonomic group at the OTU level. Arrows depict the direction of the relationship (source to target) based on the β calculation from GLM analysis. Green and red connections indicate the relative strength of the positive and negative relationships, respectively. Only 1242 interactions where 16 OTUs including two OTUs corresponding to Staphylococcus were involved were shown. B The relative abundance of two groups (11 OTUs and OTU0001) over 8-week period including before, during, and after S. aureus CM was compared in healthy quarters (n = 10) and quarters with clinical mastitis (n = 11)