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Table 1 Anthropometric data of animals used in this study

From: The influence of maternal unhealthy diet on maturation of offspring gut microbiota in rat

 

Group (n)

Body weight (g)

Diet day 30

Body weight (g)

At mating

Body weight (g)

At weaning

RP fat (g) at kill

(1d post-weaning)

Mothers

Chow (11)

278.7 ± 3.5

282.7 ± 8.3

393.4 ± 7.8

2.93 ± 0.24

 

Caf (9)

336.2 ± 7.2****

347.2 ± 11.3***

393.8 ± 8.7

4.38 ± 0.56*

Weanlings

Group (N; M/F)

Body Weight (g) (male; female)

RP fat (g) (male; female)*#

 

Chow mother (21;10/11)

45.91 ± 2.33

43.95 ± 1.97

0.07 ± 0.01

0.05 ± 0.01

 

Caf mother (16;9/7)

42.14 ± 1.28

39.83 ± 1.25

0.17 ± 0.02

0.09 ± 0.01

7 weeks

Group (N; M/F)

Body Weight (g) (male; female)##ϮϮ

RP fat (g) (male; female)

 

ChowChow (21;11/10)

370.4 ± 7.8

226.7 ± 5.5

n/a

n/a

 

ChowCaf (22;12/10)

411.5 ± 12.3

274.8 ± 8.0

n/a

n/a

 

CafChow (17;9/8)

370.7 ± 6.2

227.1 ± 4.8

n/a

n/a

 

CafCaf (16;9/7)

433.0 ± 9.8

276.0 ± 5.8

n/a

n/a

14 weeks

Group (N; M/F)

Body weight (g) (male; female)*##ϮϮ

RP fat (g) (male; female) ##ϮϮ

 

ChowChow (22;11/11)

581.2 ± 12.8

309.5 ± 9.6

4.31 ± 0.40

2.64 ± 0.58

 

ChowCaf (22;11/11)

724.1 ± 24.4

435.8 ± 32.2

12.96 ± 0.84

7.20 ± 0.77

 

CafChow (24;13/11)

619.0 ± 11.3

312.9 ± 10.1

5.52 ± 0.55

2.62 ± 0.37

 

CafCaf (26;13/13)

794.1 ± 17.6

433.7 ± 16.6

15.19 ± 0.93

6.14 ± 0.37

  1. Data are displayed as mean ± SEM
  2. Mothers: Body weight across time was analysed by mixed repeated measures ANOVA with Sidak’s multiple comparisons test and Retroperitoneal (RP) fat was analysed by independent t-test. Main effect of maternal diet ****p < 0.0001; ***p < 0.001; *p < 0.05
  3. Weanlings: Body weight and Retroperitoneal fat (RP) were analysed by two-way ANOVA. *p < 0.01 main effect of maternal diet; #p < 0.01 main sex effect
  4. 7 and 14 weeks: Body weight and RP fat (14 weeks only) were analysed by three-way ANOVA. *p < 0.05 main effect of maternal diet;##p < 0.01 main effect of sex; ϮϮp < 0.01 main effect of postnatal diet
  5. Postweaning group names denote maternal and postweaning offspring diets, respectively; for example, ‘ChowCaf’ rats were from chow dams and switched to Caf postweaning