Pathway | Total | Expected | Hits | P. Value | FDR |
---|---|---|---|---|---|
Metabolism of xenobiotics by cytochrome P450 | 66 | 0.287 | 6 | 3.35E-07 | 0.000105 |
Chemical carcinogenesis | 94 | 0.409 | 6 | 2.75E-06 | 0.000432 |
Drug metabolism– cytochrome P450 | 68 | 0.296 | 5 | 1.01E-05 | 0.00106 |
Biosynthesis of amino acids | 78 | 0.34 | 5 | 1.98E-05 | 0.00156 |
Drug metabolism– other enzymes | 87 | 0.379 | 5 | 3.37E-05 | 0.00212 |
Metabolic pathways | 1490 | 6.49 | 17 | 5.91E-05 | 0.00309 |
Glutathione metabolism | 64 | 0.279 | 4 | 0.00016 | 0.00719 |
Platinum drug resistance | 77 | 0.335 | 4 | 0.000328 | 0.0129 |
Glycine, serine and threonine metabolism | 40 | 0.174 | 3 | 0.000672 | 0.0234 |
Insulin signaling pathway | 40 | 2.09 | 10 | 0.00238 | 0.00062 |
Fluid shear stress and atherosclerosis | 143 | 0.623 | 4 | 0.0033 | 0.104 |
Bile secretion | 72 | 0.313 | 3 | 0.00369 | 0.105 |
AMPK signaling pathway | 29 | 1.51 | 8 | 0.00398 | 0.00138 |
Folate biosynthesis | 26 | 0.113 | 2 | 0.00561 | 0.147 |
Carbon metabolism | 120 | 0.522 | 3 | 0.015 | 0.363 |
Riboflavin metabolism | 8 | 0.0348 | 1 | 0.0343 | 0.77 |
Vitamin B6 metabolism | 9 | 0.0392 | 1 | 0.0385 | 0.807 |