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Table 1 Metabolic pathways of gallus gallus and mus musculus fed with methionine-restricted diets

From: Dietary L-Methionine modulates the gut microbiota and improves the expression of tight junctions in an in vitro model of the chicken gastrointestinal tract

Pathway

Total

Expected

Hits

P. Value

FDR

Metabolism of xenobiotics by cytochrome P450

66

0.287

6

3.35E-07

0.000105

Chemical carcinogenesis

94

0.409

6

2.75E-06

0.000432

Drug metabolism– cytochrome P450

68

0.296

5

1.01E-05

0.00106

Biosynthesis of amino acids

78

0.34

5

1.98E-05

0.00156

Drug metabolism– other enzymes

87

0.379

5

3.37E-05

0.00212

Metabolic pathways

1490

6.49

17

5.91E-05

0.00309

Glutathione metabolism

64

0.279

4

0.00016

0.00719

Platinum drug resistance

77

0.335

4

0.000328

0.0129

Glycine, serine and threonine metabolism

40

0.174

3

0.000672

0.0234

Insulin signaling pathway

40

2.09

10

0.00238

0.00062

Fluid shear stress and atherosclerosis

143

0.623

4

0.0033

0.104

Bile secretion

72

0.313

3

0.00369

0.105

AMPK signaling pathway

29

1.51

8

0.00398

0.00138

Folate biosynthesis

26

0.113

2

0.00561

0.147

Carbon metabolism

120

0.522

3

0.015

0.363

Riboflavin metabolism

8

0.0348

1

0.0343

0.77

Vitamin B6 metabolism

9

0.0392

1

0.0385

0.807